NCL TESTING
Below are the NCL Testing Definitions and Breeding Risk Guidelines:

TEST RESULT DEFINITIONS:

CLEAR

This finding indicates that the gene is not present in your dog.

Therefore, when used for breeding,

a Clear dog will not pass on the disease gene.


CARRIER

This finding indicates that one copy of the disease gene is present in your dog,

but that it will not exhibit disease symptoms.

Carriers will not have medical problems as a result.

Dogs with Carrier status can be enjoyed without the fear of

 developing medical problems but will pass on the disease gene 50% of the time.


AFFECTED

This finding indicates that two copies of the disease gene are present in the dog.

Unfortunately, the dog will be medically affected by the disease.

Appropriate treatment should be pursued by consulting a veterinarian.


BREEDING RISKS:

CLEAR X CLEAR = 100% CLEAR
Ideal Breeding Pair. Puppies will not have the disease gene

(neither as Carrier nor as Affected).
 

CLEAR X CARRIER = 50% CLEAR 50% CARRIER
Breeding Is Safe. No Affected puppies will be produced. However,

some of the puppies will be Carriers.
Accordingly, it is recommended that Carrier dogs

which are desirable for breeding be bred with Clear dogs in the future,

which will produce 50% carrier and 50% clear animals,

to further reduce the disease gene frequency.
These offspring should be tested for this defective gene,

and if possible, only the clear animals in this generation should be used
 

CARRIER X CARRIER = 25% CLEAR 50% CARRIER 25% AFFECTED
High Risk Breeding. Some puppies are likely to be Carriers

and some puppies are likely to be Affected.

Even though it is possible that there will be some clear puppies when

 breeding "Carrier to Carrier", in general,

 neither this type of breeding pair nor

"Carrier to Affected" are recommended for breeding.
 

CARRIER X AFFECTED = 50% CARRIER 50% AFFECTED
Breeding Not Recommended. -

All puppies will be genetically and medically affected
 

AFFECTED X AFFECTED = 100% AFFECTED
Breeding Not Recommended. -

All puppies will be medically affected

Bluebloods American Bulldogs - 2005